Embryo Freezing: Everything About Preserving Fertility

Written by

Arva Health Team

16-Sept-2024

Embryo Freezing: Everything About Preserving Fertility
Embryo Freezing: Everything About Preserving Fertility
Embryo Freezing: Everything About Preserving Fertility

Embryo freezing, also known as embryo cryopreservation, has become an increasingly popular option for individuals and couples looking to preserve their fertility. Whether you're facing medical treatments that may impact your reproductive health or simply want to delay starting a family, embryo freezing offers a way to safeguard your future parenthood dreams. In this comprehensive guide, we'll explore everything you need to know about embryo freezing, from the process itself to how it compares with egg freezing.

What Is Embryo Freezing?

Embryo freezing is a process where embryos created through in vitro fertilization (IVF) are preserved at extremely low temperatures for future use. This technique allows individuals or couples to store their embryos for months or even years before attempting pregnancy.

The process begins with ovarian stimulation and egg retrieval, followed by fertilization of the eggs with sperm in a laboratory. The resulting embryos are then frozen using advanced cryopreservation techniques, typically at the blastocyst stage (day 5 or 6 of development).

At Arva Health, we understand that embryo freezing is a significant decision. We offer comprehensive consultations to help you understand if this option is right for you. Our team of fertility specialists will guide you through each step of the process, ensuring you're fully informed and comfortable with your choice.

How Embryo Freezing Works?

The embryo freezing process involves several steps:

  1. Ovarian stimulation: Fertility medications are used to stimulate the ovaries to produce multiple eggs.

  2. Egg retrieval: A minor surgical procedure is performed to collect the mature eggs.

  3. Fertilization: The retrieved eggs are fertilized with sperm in the laboratory, either from a partner or a sperm donor.

  4. Embryo culture: The fertilized eggs are monitored as they develop into embryos over 5-6 days.

  5. Freezing: Viable embryos are frozen using a technique called vitrification, which rapidly cools the embryos to prevent ice crystal formation.

  6. Storage: The frozen embryos are stored in liquid nitrogen at -196°C (-320.8°F) until needed.

When the individual or couple is ready to use the frozen embryos, they are thawed and transferred to the uterus in a process called a frozen embryo transfer (FET).

Egg Freezing vs Embryo Freezing

One of the most common questions people have is about the difference between egg freezing and embryo freezing. While both are methods of fertility preservation, there are some key differences:


Egg Freezing:

  • Involves freezing unfertilized eggs

  • Does not require sperm at the time of freezing

  • Allows for more flexibility in future partner choice or use of donor sperm

  • May result in fewer viable embryos when thawed and fertilized


Embryo Freezing:

  • Involves freezing fertilized eggs (embryos)

  • Requires sperm at the time of freezing

  • Provides more certainty about the number of potential future pregnancies

  • May have higher success rates when thawed and transferred

Egg Freezing vs Embryo Freezing Success Rates

Success rates for both egg freezing and embryo freezing have improved significantly in recent years, thanks to advances in cryopreservation techniques. However, embryo freezing generally has higher success rates:

Embryo freezing: The survival rate of thawed embryos is typically around 95%. The live birth rate per transfer of frozen embryos is approximately 43% for women under 35, decreasing with age.

Egg freezing: The survival rate of frozen eggs after thawing is about 90%. The live birth rate per transfer using frozen eggs is approximately 50% for women under 35, also decreasing with age.

It's important to note that success rates can vary depending on factors such as age, overall health, and the quality of the eggs or embryos at the time of freezing.

Can You Freeze Eggs and Embryos at the Same Time?

Yes, it is possible to freeze both eggs and embryos during the same IVF cycle. This approach, sometimes called "split freezing," can offer the best of both worlds:

  1. Some eggs are fertilized and frozen as embryos.

  2. The remaining eggs are frozen unfertilized.

This strategy provides flexibility for future family planning while also potentially maximizing the chances of a successful pregnancy. However, it's important to discuss this option with your fertility specialist to determine if it's the right choice for your specific situation.

At Arva Health, we offer the option of split freezing. If you're unsure about whether to freeze eggs or embryos, this could be a good compromise. We'll discuss the pros and cons of this approach during your consultation and help you make an informed decision based on your individual circumstances and future plans.

The Benefits of Embryo Freezing

Embryo freezing offers several advantages:

  1. Preserves fertility: It allows individuals to delay parenthood without compromising their chances of having biological children.

  2. Increases IVF success rates: By allowing for multiple embryo transfer attempts from a single egg retrieval cycle, it can improve overall IVF success rates.

  3. Reduces health risks: It minimizes the need for repeated ovarian stimulation and egg retrieval procedures.

  4. Provides genetic testing options: Embryos can be tested for genetic abnormalities before freezing, potentially increasing the chances of a healthy pregnancy.

  5. Offers flexibility: It allows for family planning around career goals, relationship status, or medical treatments.

Risks of Embryo Freezing

While embryo freezing is generally considered safe, there are some potential risks to consider:

  1. Emotional stress: The process can be emotionally challenging, especially if there are ethical concerns about unused embryos.

  2. Financial costs: Embryo freezing and storage can be expensive, and may not be covered by insurance.

  3. Potential embryo loss: Although rare, there is a small risk of embryos not surviving the freezing or thawing process.

  4. Multiple pregnancies: If multiple embryos are transferred, there's an increased risk of multiple pregnancies, which can carry health risks for both mother and babies.

  5. Ethical considerations: Decisions about unused embryos can be complex and may raise ethical questions for some individuals or couples.

Conclusion

Embryo freezing is a powerful tool for fertility preservation, offering individuals and couples the opportunity to safeguard their future family-building options. While it comes with its own set of considerations and potential challenges, advances in technology have made it an increasingly successful and popular choice.

If you're considering embryo freezing, it's crucial to consult with a fertility specialist who can provide personalized advice based on your individual circumstances. They can help you weigh the pros and cons, understand the process in detail, and make an informed decision about whether embryo freezing is the right choice for you.

At Arva Health, we're here to support you every step of the way on your fertility journey. Our team of specialists is ready to provide personalized care, answer all your questions, and help you make the best decision for your future. We offer flexible scheduling for consultations, so don't hesitate to reach out and take the first step towards preserving your fertility options.

FAQs

1. How long can embryos remain frozen?

Embryos can remain frozen indefinitely. The longest reported successful use of frozen embryos resulted in a live birth after 27 years of storage. However, most clinics recommend using frozen embryos within 5-10 years for optimal results

2. What happens to unused frozen embryos?

Couples have several options for unused frozen embryos:

  • Keep them in storage for future use

  • Donate them to other couples or for research

  • Thaw and discard them

  • Use them in a compassionate transfer (transfer during a non-fertile period)

  • The decision is personal and can be complex, so many clinics offer counseling to help couples make this choice.

3. Is there an age limit for using frozen embryos?

While there's no universal age limit, many clinics have their own guidelines. Generally, the age limit for the woman carrying the pregnancy is around 50-55 years old, considering health risks associated with pregnancy at advanced maternal age. However, this can vary depending on individual health status and clinic policies.

4. Can I use my frozen embryos with a gestational carrier?

Yes, frozen embryos can be used with a gestational carrier. This is an option for women who are unable to carry a pregnancy themselves due to medical reasons or for same-sex male couples.

5. What's the cost of embryo freezing and storage?

The cost can vary widely depending on location and specific clinic fees. On average, the initial freezing process can cost between $7,000-$12,000. Annual storage fees typically range from $500-$1,000 per year. It's important to check with your specific clinic for accurate pricing and to inquire about any available financing options or insurance coverage.

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Pioneering fertility care, reimagined for India—on your terms.

This site is for informational purposes only and not a substitute for medical advice, diagnosis, or treatment. If you're looking for medical advice, we suggest talking with a qualified physician.

55, 4th A Main, 5th Block, Koramangala, Bangalore, 560095

© 2024 Arva Health

Pioneering fertility care, reimagined for India—on your terms.

This site is for informational purposes only and not a substitute for medical advice, diagnosis, or treatment. If you're looking for medical advice, we suggest talking with a qualified physician.

55, 4th A Main, 5th Block, Koramangala, Bangalore, 560095

© 2024 Arva Health

Pioneering fertility care, reimagined for India—on your terms.

This site is for informational purposes only and not a substitute for medical advice, diagnosis, or treatment. If you're looking for medical advice, we suggest talking with a qualified physician.

55, 4th A Main, 5th Block, Koramangala, Bangalore, 560095

© 2024 Arva Health