Does DHEA-S Help With Female Fertility?

DHEA-S and Female Fertility: A Guide

Fertility supplements are often an add on during an IVF or egg freezing journey.

Especially with female fertility, a lower ovarian reserve is on the harder end to treat.

Among the few options that have been proposed to treat this, dehydroepiandrosterone sulfate (DHEA-S) has emerged as a supplement with a potential role in boosting female fertility.

This article delves into the current research around DHEA-S, exploring its connection snd potential benefits to female reproductive health and fertility.

What is DHEA-S?

Dehydroepiandrosterone sulfate (DHEA-S) is a hormone produced by the adrenal glands, acting as a fundamental building block for other crucial hormones in the body. DHEA-S serves as a precursor, primarily converting into androgens and estrogens.

While closely related to dehydroepiandrosterone (DHEA), they are distinct forms. DHEA-S, the sulfated version, is found in much higher concentrations in the bloodstream.

As women age, DHEA-S levels naturally decline. This decrease can coincide with a decline in fertility potential. This natural correlation has sparked interest in the potential of DHEA-S supplementation to influence female fertility.

What is the impact of DHEA-S on female fertility?

Research on the role of DHEA-S in female fertility is ongoing, compared to studies on DHEA. However, some studies have explored the potential effects of DHEA-S supplementation on reproductive health:

1. Enhanced ovarian function: Some research suggests that DHEA-S may play a role in improving ovarian function and follicular development, which are crucial aspects of female fertility. By promoting ovarian health, DHEA-S supplementation may theoretically enhance the chances of successful conception.

2. Support for hormonal balance: Hormonal imbalances, such as disruptions in estrogen and androgen levels, can impact reproductive health and fertility. DHEA-S, as a precursor to these hormones, may help support hormonal balance, potentially addressing underlying factors contributing to infertility.

3. Potential benefits for women with Diminished Ovarian Reserve: Diminished ovarian reserve (DOR) is a common concern for women facing fertility challenges, particularly as they age. Some studies have suggested that DHEA-S supplementation may benefit women with DOR by improving ovarian response to fertility treatments such as in vitro fertilization (IVF) and potentially increasing the likelihood of successful pregnancy.

What to consider before taking DHEA-S supplements?

Before considering DHEA-S supplementation for fertility purposes, individuals should consult with a qualified healthcare provider. Some important considerations include:

• Potential side effects: Like any supplement or hormone therapy, DHEA-S supplementation may be associated with side effects and risks, including acne, hair growth, and mood changes. Individuals with certain medical conditions or those taking medications should exercise caution and seek medical advice before starting DHEA-S supplementation.

• Consider a personalised treatment approach: Fertility treatment should be individualised based on a comprehensive assessment of each person's medical history, reproductive health status, and specific fertility concerns. A healthcare provider can offer personalised guidance and recommendations tailored to your unique needs and circumstances.

• Take a comprehensive fertility evaluation: Before initiating any fertility treatment, individuals should undergo a thorough fertility evaluation to identify potential underlying factors contributing to infertility. This evaluation may include assessments of ovarian reserve, hormonal testing, and reproductive anatomy, among other factors.

How Arva can help with your fertility journey

Understanding your hormonal profile is a crucial step in optimising your fertility journey.

Arva's comprehensive at-home fertility test provides valuable insights into your ovarian reserve by measuring Anti-Müllerian Hormone (AMH) levels, which is a well-established indicator of your remaining egg pool.

In addition to AMH, our complete fertility test measures other key hormones like FSH and estradiol.

This information can be particularly beneficial to understand your overall reproductive health before starting DHEA-S supplementation.

With this, you can have a chat with your doctor about whether supplementation might be right for you and how it might impact your individual hormone profile.

At Arva, we’re here to help you make more informed, empowered decisions ❤️